Vardenafil is one of the most popular impotence pills. It can last up to 5 hours in your body! Learn more about how it works!

Vardenafil pills – Overview

Vardenafil is one of the four PDE5 inhibitors used to treat erectile dysfunction (ED), a condition that happens when a man isn’t able to get and maintain an erection. The other components of this group are sildenafil (Viagra), tadalafil (Cialis), and avanafil (Stendra). Levitra is the brand name of vardenafil. 

You’ve probably heard of this impotence treatment, but how exactly does it work and how long does vardenafil last in your body? Let’s discuss more these aspects, as well as its side effects, contraindications, and drug interactions.

How does vardenafil work?

Vardenafil, the active ingredient found in Levitra, relaxes your blood vessels and increases blood flow to your penis. As a result, you are able to get and sustain an erection, long enough to satisfy your partner. Keep in mind that the substance works only in response to sexual stimulation, so foreplay is still necessary in order to reach optimal results. 

How to use the pill

One of the main characteristics that differentiate one ED treatment from another is its dosage availability. Vardenafil comes in strengths of 5, 10, and 20 mg. One Levitra tablet should be taken when needed, 30-60 minutes before sexual intercourse. Typically, vardenafil 10 mg is the starting dose, allowing your prescribing physician to decrease or increase it, according to the way you respond to it.

On the other hand, Cialis, for instance, is available in dosages of tadalafil 2.5 mg and can be used daily, not necessarily before intercourse. The active substance stays in your body for up to 36 hours! You should keep in mind that ED medications can be taken with a glass of water, but alcohol is not recommended. To explain, alcohol can increase the risk of adverse effects. Also, you may take the drug with food, but the high fat meal can delay the effects of Levitra. 

How long does vardenafil last in your body?

So how long does vardenafil last in your bloodstream after you take the pill? The average period that Vardenafil’s effects last in your body is about 4 or 5 hours. This time counts for any of the available doses of the drug. Viagra has the same effect duration, while Stendra can last up to 6 hours, and Cialis up to 36 hours. All of them are prescription drugs, so typically, the doctors or pharmacists prescribe you the suitable dosage and medication according to various factors, like your medical history or sexual activity frequency.

Please note that you should take a maximum of one Levitra tablet every 24 hours! Stick to the instructions given by your health expert to minimize the risk of unwanted side effects.


Unwanted side effects and interactions can occur when you use erectile dysfunction drugs, including Levitra. The most common adverse effects are:

  • Nausea
  • Flushing
  • Upset stomach
  • Indigestion
  • Headache

More serious side effects include chest pain or painful erection. In general, the side effects of this drug are mild and go away on their own. However, if any symptoms are troublesome and long-lasting, you should contact your doctor immediately. 

Do not take vardenafil in case you have or have had any of the following medical conditions:

  • Hypersensitivity to vardenafil
  • A recent heart attack
  • Heart problems
  • High or low blood pressure
  • Severe liver disease
  • Irregular heart rhythm

Vardenafil can also interact with a series of medications, increasing the risk of adverse effects. Do not combine this ED treatment with antibiotics, anti-fungal drugs, nitrates, or alpha-blockers for prostate or blood pressure problems. 

Disclose to your doctor if you are using herbal supplements, as well. To explain, certain herbal supplements, like arginine, combined with vardenafil can cause the nitric oxide in your blood to become too high, making your blood pressure drop significantly. Ultimately, this can cause you to become lightheaded or pass out. 

Check the Patient Information Leaflet of the product for detailed information on side effects, contraindications, and interactions.

Key Takeaways

Vardenafil is a PDE5 inhibitor and one of the most popular ED medications. It comes in strengths of 5, 10, 20 mg, but only a health expert can prescribe the right dosage for you. How long does vardenafil last? The answer depends on a lot of factors, but the drug can remain in your bloodstream for up to 6 hours when taken exactly as instructed. Since it contains an active substance, you should pay attention to its side effects, contraindications, and drug interactions before using it.